SURGILAST® (Azelastine Hydrochloride 0.05%) is a sterile ophthalmic solution Azelastine hydrochloride is a relatively selective histamine H1 antagonist and an inhibitor of the release of histamine and other mediators from cells (e.q. mast cells) involved in the allergic response. Based on in-vitro studies using human cell lines, inhibition of other mediators involved in allergic reactions (e.g. leukotrienes and PAF) has been demonstrated with azelastine hydrochloride. Decreased chemotaxis and activation of eosinophils has also been demonstrated.
SURGILAST® (Azelastine Hydrochloride Ophthalmic Solution) 0.05% W/V is indicated for the treatment of itching of the eye associated with allergic conjunctivitis.
The recommended dosage of SURGILAST Ophthalmic Solution is one drop in each affected eye twice a day.
SURGILAST® (azelastine ophthalmic solution) 0.05% is supplied sterile in opaque white LDPE plastic bottle with dropper with white high impact polystyrene (HIPS) cap in 5ml pack.